PARDS
Collection of relevant journal articles
Pediatric acute respiratory distress syndrome: consensus recommendations from the Pediatric Acute Lung Injury Consensus Conference - PubMed PALICC
Pediatric acute lung injury: prospective evaluation of risk factors associated with mortality - PubMed
( Flori, Glidden, Rutherford and Matthay, 2005)
'Lumping or splitting' in paediatric acute respiratory distress syndrome (PARDS) - PubMed
( De Luca, Harrison and Peters, 2018)
Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study - PubMed
( Khemani, Smith, Lopez-Fernandez, Kwok, Morzov, Klein, Yehya, Willson, Kneyber, Lillie, Fernandez, Newth, Jouvet, Thomas, et al., 2019)
Adherence to Lung-Protective Ventilation Principles in Pediatric Acute Respiratory Distress Syndrome: A Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Study - PubMed
( Bhalla, Klein, Emeriaud, Lopez-Fernandez, Napolitano, Fernandez, Al-Subu, Gedeit, Shein, Nofziger, Hsing, Briassoulis, Ilia, Baudin, Piñeres-Olave, Izquierdo, Lin, Cheifetz, Kneyber, Smith, Khemani, Newth et al, 2021)
Epidemiology and Outcomes of Critically Ill Children at Risk for Pediatric Acute Respiratory Distress Syndrome: A Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology Study - PubMed
( Shein, Maddux, Klein, Bhalla, Briassoulis, Dahmer, Emeriaud, Flori, Gedeit, Ilia, Kneyber, Napolitano, Ohshimo, Pons-Òdena, Rubin, White, Yehya, Khemani and Smith, 2022)
Phenotypes/Personalised pARDS medicine
Circulating markers of endothelial and alveolar epithelial dysfunction are associated with mortality in pediatric acute respiratory distress syndrome - PubMed
( Yehya, Thomas, Meyer, Christie, Berg and Margulies, 2016)
Identification of phenotypes in paediatric patients with acute respiratory distress syndrome: a latent class analysis - PubMed
( Dahmer, Yang, Zhang, Quasney, Sapru, Weeks, Sinha, Curley, Delucchi, Calfee, Flori, 2022)
Peripheral blood transcriptomic sub-phenotypes of pediatric acute respiratory distress syndrome - PubMed
( Yehya, Varisco, Thomas, Wong, Christie and Feng, 2020)
Promises and challenges of personalized medicine to guide ARDS therapy - PubMed
( Wick, McAuley, Levitt, Beitler, Annane, Riviello, Calfee and Matthay, 2021)
Inhaled Nitric Oxide
The effect of inhaled nitric oxide in acute respiratory distress syndrome in children and adults: a Cochrane Systematic Review with trial sequential analysis - PubMed
( Karam, Gebistorf, Wetterslev and Afshari, 2016)
The Association Between Inhaled Nitric Oxide Treatment and ICU Mortality and 28-Day Ventilator-Free Days in Pediatric Acute Respiratory Distress Syndrome - PubMed
( Bhalla, Yehya, Mack, Wilson, Khemani and Newth, 2018)
ECMO
UK collaborative randomised trial of neonatal extracorporeal membrane oxygenation. UK Collaborative ECMO Trial Group - PubMed
Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trial - PubMed
( Peek, Mugford, Tiruvoipati, Wilson, Allen, Thalanany, Hibbert, Truesdale, Clemens, Cooper, Firmin and Elbourne, 2009)
Referral to an extracorporeal membrane oxygenation center and mortality among patients with severe 2009 influenza A(H1N1) - PubMed
( Noah, Peek, Finney, Griffiths, Harrison, Grieve, Sadique, Sekhon, McAuley, Firmin, Harvey, Cordingley, Price, Vuylsteke, Jenkins, Noble, Bloomfield, Walsh, Perkins, Menon, Taylor and Rowan, 2011)
Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome - PubMed [EOLIA]
Collection of relevant journal articles
Recommendations for mechanical ventilation of critically ill children from the Paediatric Mechanical Ventilation Consensus Conference (PEMVECC) - PubMed
( Kneyber, de Luca, Calderini, Jarreau, Javouhey, Lopez-Herce, Hammer, Macrae, Markhorst, Medina, Pons-Odena, Racca, Wolf, Biban, Brierley and Rimensberger, 2017)
PEEP, HFOV, APRV
Positive End-Expiratory Pressure Lower Than the ARDS Network Protocol Is Associated with Higher Pediatric Acute Respiratory Distress Syndrome Mortality - PubMed
( Khemani, Parvathaneni, Yehya, Bhalla, Thomas and Newth, 2018)
Effect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial - PubMed
( Cavalcanti, Suzumura, Laranjeira, et al. 2017)
Do We Really Know How to Use High-Frequency Oscillatory Ventilation in Critically Ill Children? - PubMed
( Kneyber and Markhorst, 2016)
Airway Pressure Release Ventilation in Pediatric Acute Respiratory Distress Syndrome. A Randomized Controlled Trial - PubMed
( Ganesan, Jayashree, Singhi and Bansal, 2018)
--------------------------------------------------------------------------------------------------
Early Use of Adjunctive Therapies for Pediatric Acute Respiratory Distress Syndrome: A PARDIE Study - PubMed
( Rowan, Klein, Hsing, Dahmer, Spinella, Emeriaud, Hassinger, Piñeres-Olave, Flori, Haileselassie, Lopez-Fernandez, Chima, Shein, Maddux, Lillie, Izquierdo, Kneyber, Smith, Khemani, Thomas and Yehya, 2020)
Neuromuscular blockade
Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome - PubMed NHLBI: ROSE
Early Neuromuscular Blockade in Moderate-to-Severe Pediatric Acute Respiratory Distress Syndrome - PubMed
( Rudolph, Kneyber, Asaro, Cheifetz, Wypij and Curley, 1970)
Paediatric Acute Respiratory Distress Syndrome Neuromuscular Blockade study (PAN-study): a phase IV randomised controlled trial of early neuromuscular blockade in moderate-to-severe paediatric acute respiratory distress syndrome - PubMed
( Rudolph, Slager, Burgerhof, van Woensel, Alffenaar, Wösten, de Hoog, IJland and Kneyber, 2022)
Steroids
Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial - PubMed
( Villar, Ferrando, Martínez, Ambrós, Muñoz, Soler, Aguilar, Alba, González-Higueras, Conesa, Martín-Rodríguez, Díaz-Domínguez, Serna-Grande, Rivas, Ferreres, Belda, Capilla, Tallet, Añón, Fernández and González-Martín, 2020)
Improved oxygenation following methylprednisolone therapy and survival in paediatric acute respiratory distress syndrome - PubMed
( Mitting, Ray, Raffles, Egan, Goley, Peters and Nadel, 2019)
Prone
Unproven and Expensive before Proven and Cheap: Extracorporeal Membrane Oxygenation versus Prone Position in Acute Respiratory Distress Syndrome - PubMed
( Li, Scales and Kavanagh, 2018)